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Overview
Aspira's PMI materials
offer many unique advantages, including:
- Predictable separation of known and
unknown proteins via sequence-based capture.
- Proteins can be captured through
an interaction with a domain or region of the protein that is
essential to its function.
- Captured proteins can
retain correct folding, post-translational modifications and activity.
- High
specificity
due to a low tolerance for mismatch.
- High
affinities
comparable to good antibodies.
- Polymer-based capture facilitates detection using
direct fluorescence tags, ELISA, mass spectrometry, or other proven
detection methodologies.
- Easy-to-generate using a self-assembling
universal monomer matrix.
Capture agents can usually be generated within 3 weeks without
purified target protein. Crosslinked polymer is very stable.
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